I like this a lot. I also interpret it as you're slowly losing yourself to the depression and fading away into nothingness. Like the despair is so vast that you can't hold yourself together anymore and you're dispersing. This looks really cool. I love the textures you used and how most of the face is washed out. The black background was a good call, too. Good job on this.
It is like fading away into nothingness, a lot like losing the ability to hold yourself together. That's a perfect description.
I like how the depression seems to be pulling at model. Nicely done.